Genetic mouse models of migraine
نویسندگان
چکیده
منابع مشابه
Genetic models of migraine.
Migraine is a common, disabling, complex brain disorder, presenting in attacks that may have up to 3 phases: a prodromal phase, the aura phase, and the headache phase. The pathogenesis of the aura and headache phases is reasonably well understood, but the mechanism by which migraine attacks are triggered is unknown. Most likely, migraineurs have a genetically determined reduced threshold for mi...
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Migraine is a common, disabling, and undertreated episodic brain disorder that is more common in women than in men. Unbiased genome-wide association studies have identified 13 migraine-associated variants pointing at genes that cluster in pathways for glutamatergic neurotransmission, synaptic function, pain sensing, metalloproteinases, and the vasculature. The individual pathogenetic contributi...
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ژورنال
عنوان ژورنال: The Journal of Headache and Pain
سال: 2019
ISSN: 1129-2369,1129-2377
DOI: 10.1186/s10194-019-1029-5